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Animals were kept at room temperature (22 C 3 C) in 50% (20%) humidity with a 12 h/12 h day/light cycle throughout the experiment

* Correspondence: Xun Wu, [email protected] These authors have contributed equally to this work ORCID: Tanwei Fang, orcid.org/0009-0006-0404-7553 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers


Many of the side effects seem to be due to overdosing