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Gut flora-dependent Metabolite Trimethylamine-N-Oxide Accelerates Endothelial Cell Senescence and Vascular Aging through Oxidative Stress

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(B) ROS level in basal condition (5% FBS) or serum-deprived HMVECs treated with PBS (vehicle, 12h), plumbagin (10M in PBS, 12h), siNox4 or non-targeting siRNA (Ctr siRNA)

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doi: 10.1213/ane.0b013e318167ad77

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Mehta SH, Cox A, Hoover DR, Wang X, Mao Q, Ray S, et al

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