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When mice were monocolonized with bacteria known to induce T cells in the wall of the gut, there was an apparent reduction in neuronal density in the myenteric plexus, a reduction in nerve fibers projecting to the mucosa, and downregulation of a number of neurotransmitter transcripts including Nos1 , Vip , Calcb , and Tac1 , which encode NOS, VIP, CGRP-, and substance P, respectively

Microalbuminuria, which is defined as a urinary albumin excretion ranging from 30 to 300 mg in a 24-hour urine collection, generally precedes overt nephropathy by 5 to 10 years

Mechanisms associated with physical stress and tissue integrity

The Too Much, Too Soon Effect If you only floss before a dentist appointment, your gums will almost definitely bleed once you restart

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