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Possible Skin Reactions Some individuals may experience mild irritation or sensitivity, particularly when using high concentrations or poorly formulated products

Other Dietary Sources Worth Noting While concentrations are considerably lower than in mushrooms, ergothioneine can also be found in: Animal products: Liver (especially kidney and red blood cells contain moderate amounts) These levels reflect the ergothioneine animals consumed from their own diets Legumes: Black beans, kidney beans, and red beans (especially when grown with mycorrhizal fungi) A 2023 study found black beans showed up to 72 times more ergothioneine when grown with beneficial soil fungi [2] Grains and fermented foods: Oat bran and wheat (particularly when cultivated with specific soil fungi) Tempeh, natto, miso, kimchi, and sauerkraut contain small amounts Spirulina contains relatively high amounts compared to other non-fungal sources Typical dietary intake ranges from 5-20 mg per day depending on mushroom consumption patterns

Higher oxidation states of sulfur, such as sulfonyls found in sulfonylureas and sulfonylamides, are significantly more hydrophilic, which facilitates their elimination

Powder formulas are better for quality control because they are easy to test analytically and stay stable for longer

Genomics 2012 pii: S0888-7543(12)00228-5