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Peer review Peer review information Nature thanks Ashwin Ananthakrishnan, Andrew Mertens, Siddharth Singh and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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DAB staining produces a distinct dark brown precipitate in the presence of peroxidases found in red blood cells, enabling precise identification of extravasated blood cells within the brain parenchyma [18]

The interactions between the ENS, gut immunity, and the gut microbiota are indispensable to maintaining intestinal barrier function and preventing disease progression

2 Body weight (kg) by week