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Haddad FG, Sasaki K, Bidikian A, Issa GC, Kadia T, Jain N, Alvarado Y, Short NJ, Pemmaraju N , Loghavi S, Patel KP, Kanagal-Shamanna R, Yilmaz M, Masarova L, Jabbour E, Kantarjian H

In addition, intestinal macrophages respond to ACh released by nerve fibers in the intestinal myenteric plexus, ameliorating inflammation in vivo , in a mechanism that involves the activation of Jak2/STAT3 and the transactivation of STAT3-responsive DNA elements (84)

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Bile acids can work as hormone to act on farnesoid X receptor (FXR) and G protein-coupled membrane receptor 5 (TGR5) to decrease triglyceride accumulation, fatty acid oxidation, decrease the expression of pro-inflammatory cytokines and chemokines in aorta through the inactivation of NF-B (Levi, 2016