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J Med Sci Clin Res

The computed pseudotime was overlaid onto the UMAP of D14 eosinophils to visualize transcriptional progression

Some animal and early-phase studies noted elevated inflammatory cytokines (IL-6, TNF-) at higher doses, though clinical relevance in humans at therapeutic doses remains unclear

Construction of expression plasmids for reporter proteins carrying the Azo-tag PCR was performed using the Q5 Hot Start High-Fidelity Polymerase (New England Biolabs) according to the manufacturers protocol

The current landscape of understanding, primarily based on limited clinical data and anecdotal experiences, calls for a more comprehensive and systematic approach to safety evaluation