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Myeloperoxidase-Derived Oxidants Induce Blood-Brain Barrier Dysfunction In Vitro and In Vivo
[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Su P.-W., Yang C.-H., Yang J.-F., Su P.-Y., Chuang L.-Y
A., Shamsuddin S., Johan M
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Similarly, although AMG 595 was found to be effective in GBM xenograft animal models and had favorable results during a phase I clinical study, the development of AMG-595 was discontinued because of limited efficacy [67, 68]
