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However, it is worth noting that 300 mg/day can not yet be confirmed as the optimal dose, because it is not known whether there are other possible optimal doses (the present study only compared the difference between 600 and 300 mg/day)

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However, while the final outcome of mitochondrial dysfunction is cell death, the phenotype of death (apoptosis and/or necrosis) depends on the level of cellular ATP, as ATP is required for the efficient assembly of the apoptosome

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