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Description
Studies have also examined it in models involving neuropathic and metabolic stress responses

[DOI] [PubMed] [Google Scholar] 157.Tai K, Rappolt M, He X, Wei Y, Zhu S, Zhang J, et al
Together, these findings suggest a role for GSTO1 in regulating cell signalling and redox homeostasis through affecting the S -glutathionylation status on its target proteins

Alternative activation of macrophages: Mechanism and functions
In renal biopsy tissue studies of CKD patients and mice models including UUO and renal ischemia-reperfusion injury, downregulation of GPx4 and upregulation of 4-hydroxynonenal were observed
