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When it gets to the end of a strand, its not a perfect fit on the end (the mechanics of this is a little complicated) and needs a bit of scratch DNA at the end of the strand to successfully complete the DNA replication

The combined treatment reduced HbA1c to a greater degree considering it decreased by 2.2% with the combination of semaglutide and cagrilinide, 1.8% with semaglutide alone, and 0.9% with cagrilintide [2]

Other possible side effects include infection of the site, textural changes in the skin and permanent scarring