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Nutritional immunity beyond iron: a role for manganese and zinc

By using Gateway cloning, NINJ1 cDNA from pENTR223-NINJ1 (DNASU, HsCD00505254) and SLC7A11 cDNA from pENTR223-SLC7A11 (DNASU, HsCD00512940) were individually subcloned into pLVpuro-CMV-N-EGFP (Addgene, #122848) and pLVpuro-CMV-N-mCherry (Addgene, #123221) for lentiviral expression

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However, inhibition of endonuclease activity of APE1, rather than REDOX function, could interact with NPM1 to trigger p53-mediated effects on colon cancer cell metabolism and improve its sensitivity to targeted drugs [22]

In particular, the production of acetylcholine (ACh) by choline-acetyltransferase (ChAT)-expressing B cells, which seems to be essential for efficient liver regeneration in a mouse model of partial hepatectomy (112)
