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Description
By competitively binding to p53, FOXO4-DRI displaces endogenous FOXO4, causing p53 nuclear exclusion and translocation to mitochondria where it triggers the intrinsic apoptotic pathway through caspase-3/7 activation

It primarily involves the HFE gene

refrigerate only after opening or mixing peptides (cold can sometimes reduce benzyl alcohol effectiveness over very long periods)

Commun Med

Mechanizmy angiogenezy nowotworowej
