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Less common: joint stiffness (usually resolves), carpal tunnel symptoms at higher doses, mild fasting glucose elevation

doi: 10.1089/ars.2017.7176 167 ChenDTavanaOChuBErberLChenYBaerRet al

Long-term exposure studies extending to 90 days report no mortality or severe adverse events but highlight the necessity to monitor for possible bioaccumulation and subtle organ function alterations in chronic use (Noga et al., 2023)

Tropsha A, Isayev O, Varnek A, Schneider G, Cherkasov A

10.1016/j.jep.2020.112895 [DOI] [PubMed] [Google Scholar] Chen C, Liao J, Xia Y, Liu X, Jones R, Haran J, McCormick B, Sampson TR, Alam A, Ye K (2022) Gut microbiota regulate Alzheimers disease pathologies and cognitive disorders via PUFA-associated neuroinflammation