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Description
These studies in anesthetized rabbits were undertaken to explore the possible mechanisms underlying the hemodynamic effects of hydroxocobalamin by investigating 1) possible hemodynamic effects of cyanocobalamin, which is formed on a molar-to-molar basis when hydroxocobalamin binds cyanide, and 2) the interference of hydroxocobalamin with the endothelial nitric oxide system
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Unlike larger proteins that undergo hepatic metabolism or receptor-mediated endocytosis for degradation, KLOW's primary clearance route is direct renal excretion
19575;22(5):73046
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