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Amid concerns of losing its first-mover advantage to competitors like Eli Lilly, the company also saw a change in leadership with the ousting of its CEO in May 2025

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Measures should be taken to ensure that the transplanted cells thrive within the hostile environment of a degenerating IVD by directly contributing to ECM synthesis and inducing a reparative shift in native cell activity via paracrine signaling or by facilitating the arrival of regenerative cells and preventing the infiltration of harmful cells