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However, the melatonin synthesized by extrapineal organs could not replace the function of melatonin produced by pineal gland, such as the regulation of circadian rhythms [49], the neuroprotection, and anti-inflammatory responses [50, 51]

Fujita K, Yamauchi K, Shibayama K, Ando M, Honda M, et al

Patients are encouraged to increase physical fitness, improve nutrition (including a reduction in saturated fats), abstain from smoking, and protect their eyes from excessive light

Since vitamin K is critical for the generation of gla residues in clotting factors, as described above, deficiency in this vitamin results in dysfunction in the processes of blood coagulation

Histone H3K27 Demethylase JMJD3 in Cooperation with NF-B regulates keratinocyte wound healing