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The accumulation of these PL-PUFA-OOH molecules disrupts the integrity and fluidity of the cell membrane, ultimately leading to membrane rupture, the release of the cellular contents and cell death (18)

Immune-mediated damage to peripheral nerves results from aberrant humoral and cellular responses directed against myelin or axolemmal components, leading to complement activation and inflammatory nerve injury (46) (Figure 1)

These drug conjugates combine a sustained release, different kinds of antibiotics, and antibacterial activities as well as carrier composition [47]

10 , e0173022 (2022)
