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The accumulation of these PL-PUFA-OOH molecules disrupts the integrity and fluidity of the cell membrane, ultimately leading to membrane rupture, the release of the cellular contents and cell death (18)

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Immune-mediated damage to peripheral nerves results from aberrant humoral and cellular responses directed against myelin or axolemmal components, leading to complement activation and inflammatory nerve injury (46) (Figure 1)

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These drug conjugates combine a sustained release, different kinds of antibiotics, and antibacterial activities as well as carrier composition [47]

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10 , e0173022 (2022)

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