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Accordingly, the reduction in PON1 observed in our sarcoidosis cohort likely reflects heightened oxidative stress within the granulomatous inflammatory environment but is not unique to sarcoidosis

A worldwide epidemiological study on pigmentary disorders reveals half of all people report having at least one skin pigmentation issue

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This is more challenging than the modular PKSs, as only a single set of domains is present and inactivation of either the KS or AT domain abolishes all enzyme activities
