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Genipin-crosslinked albumin nanoparticles containing neratinib and silibinin: a dual-death therapy for triple negative breast cancer

AMPK can be thought of as a key contributing factor of HIF-1 functions in response to H 2 O 2 , and it may also play a role in the complex HIF-1 regulatory mechanisms (Figure 4) [57]
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10.1186/s13046-018-0985-y J

Nanocarrierbased delivery systems (e.g., liposomes, polymeric nanoparticles, solid lipid nanoparticles) improve the solubility, bioavailability, and tumortargeting of phytochemicals, thereby enhancing their therapeutic index as adjuncts to conventional therapy (cited [184, 185, 186])
