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[DOI] [PubMed] [Google Scholar] 66.Mao Y.F., Guo Z., Zheng T., Jiang Y., Yan Y., Yin X., Chen Y., Zhang B

Ferroptosis vulnerability Metabolic status and gene mutation in cancer cells In certain cancer cells, not only the specific cellular states but also mutations in some genes will exhibit unexpected sensitivity to ferroptosis

This results in increased proteasomal degradation of oxidatively damaged proteins as well as p62, thereby facilitating ATG-lysosomal degradation of proteins and dysfunctional organelles, such as the mitochondria (Levonen et al., 2014)

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[DOI] [PMC free article] [PubMed] [Google Scholar] AbouHashem, M
