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To assess whether Cas12f delivery via EVs requires MIM, we attenuated protrusion formation by introducing a five-lysine-to-alanine (5KA) mutation in the MIM I-BAR domain 54 , which was previously shown to impair EV generation 40

Role of cytochrome c in -synuclein radical formation: implications of -synuclein in neuronal death in Maneb-and paraquat-induced model of Parkinsons disease

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Overall structure The homodimeric flavoprotein TrxR1 possesses two redox centres, both of which are required for catalysis

(63) found the upregulation of oxidative stress and c-Ha-ras in VSMCs could be reserved by CYPs and AhR inhibitor ellipticine