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FIGURE 2 4.3 Mn transport dynamics at the BBB The brain tightly regulates substances that enter and exit

Reactive astrocytes release cytokines and chemokines that further amplify the inflammatory response and disrupt the blood-brain barrier, allowing peripheral immune cells to infiltrate the CNS (Qian et al., 2023)

The mechanisms of central sensitization are rely on the pathological changes, particularly alterations in synaptic plasticity changes, within the central nervous system

The average person gets most of their vitamin D from sunlight, although fortified foods, such as milk and cereals, can also provide vitamin D

10.1021/ja00350a059
