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If you absolutely cannot avoid taking it with food, a small snack low in fat and fiber would be theoretically less disruptive than a large, heavy meal

Paired with sterility testing, this evaluation confirms that each batch is free from bacterial endotoxins

Feb 2012;95(2):297-308

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Although additional studies are warranted, the curli protein is also known to promote aggregation and neurodegeneration of amyloid-, SOD1-G85R, and huntingtin in AD, ALS, and Huntington disease models, respectively (Wang et al., 2021)