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Xu et al., 2005

GPX4 converts reduced glutathione (GSH) into oxidized glutathione (GSSH) and reduces cytotoxic lipid peroxides

43 The relevance of this pathway for tumorigenesis is demonstrated by the fact that humans with the Laron syndrome, a recessively inherited defect in the growth hormone receptor, display extremely low IGF-1 and reduced insulin concentrations and usually do not develop cancer despite high prevalence of obesity and dyslipidemia

72 MCED is a big step toward proactive, data-driven healthcarebut its not a substitute for standard screenings or diagnostic pathways that we know saves lives

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