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B12 injections have been shown to support memory, mood, cognition, depression, anxiety, and certain nerve-related pain such as low back pain and post-herpetic neuralgia (shingles)

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JAMA 2013;310:2435-42

Frequently Asked Questions Glossary References Pickart L, Margolina A

Disruptions in brain insulin signaling can adversely affect the dopaminergic mesolimbic reward circuit, altering hedonic perceptions [89, 90]