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After the results were analyzed, researchers suggested that the combination of GHRP-2 + GnRH + TRH induced the greatest apparent activation of growth hormones along thyroid stimulating hormone and luteinizing hormone axes, along with other possible metabolic effects

Authors showed upregulation of transcripts related to inflammation, wounding and defence responses, complement and coagulation and cytokinecytokine receptor interaction pathways (24)

Moreover, excessive LHCGR activation may trigger premature luteinization of granulosa cells through ERK1/2-mediated phosphorylation, disrupting dominant follicle selection

Follow up analysis using lower order ANOVA models with Bonferroni corrections and pair-wise comparisons revealed a significant time group interaction during the posttest (p=.003)

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