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The casein kinase 1/ (CK1/) and adenosine 3,5-monophosphate (AMP) kinase (AMPK) phosphorylate PER and CRY proteins, respectively, thus promoting polyubiquitination by their respective E3 ubiquitin ligase complexes, which tag PER and CRY proteins for degradation by the 26 S proteasome complex

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The NETosis induced by autophagy could be suppressed and the apoptosis induced by lipopolysaccharide-activated neutrophils was enhanced within the administration of andrographolide in vitro

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Aquaculture 439:2028 Samir SM, Abbas AM, Safwat SM, Elserougy HG (2018) Effect of l-carnitine on diabetes-induced changes of skeletal muscles in rats