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The excess accumulation of labile iron in the mitochondria of FRDA patients can react with the mitochondrial reactive oxygen species (ROS) that is inevitably present in these organelles due to occasional leakages of electron(s) from the electron transport chain (Zhao et al., 2019)

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KLOW can begin roughly 4872 hours after minor procedures, once the initial inflammatory cascade has peaked, with any new compounds held through the acute first week
