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standalone weight-loss evidence for the blend is weak and largely uncontrolled

The argument against treatment of this population stems from the neuropsychiatric side effects associated with interferon and ribavirin therapy such as depression, irritability, suicidal ideation, mania, mood swings and relapse of drug or alcohol abuse

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[DOI] [PubMed] [Google Scholar] 181

The molecule reaches plasma peak concentration (Tmax) 3-4 hours post-ingestion, with sustained supplementation protocols (typically 1-3 g/day) elevating muscle free carnitine pools by approximately 20%