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Failure to achieve adequate early CD4 + counts, such as meeting a threshold of 50 cells/L in the first 100 days, indicates an increased risk of complications, establishing a critical window of vulnerability

The hepatocarcinogenicity of peroxisome proliferators in rodents involves several members of this heterogeneous group of agents (Evans and Lake 1998)

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Indeed, dietary copper regulates SOD activity in the tissues of young developing animals

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