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While under pathological conditions, oxygen reacts with excess labile iron and generates ROS that attacks lipid membrane, implicated in lipid peroxidation (Han et al., 2020)
Presence of oxysterols in the blood (cholesterol oxides)
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Collectively, these data highlight a key role of mGSH in maintaining a healthy antioxidant system in both systems and on H 2 O 2 homeostasis