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Similarly, aflatoxin B1, a toxic metabolite produced by fungi of the genus Aspergillus, is activated by cytochromes P450 into highly reactive epoxides with mutagenic properties

& Triggle, C

Munawar et al

Transcriptomic analysis reveals the roles of detoxification systems in response to mercury in chromera velia

Subsequently, a cascade of reactions ensues, which includes the interaction of superoxides with nitric oxide (NO) to yield peroxynitrite (ONOO ) and the conversion of H 2 O 2 into water, eventually leading to the generation of hydroxyl radicals ( A significant source of ROS emerges from the end substrate of the respiratory chain, situated within the inner mitochondrial membrane