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Taken together with the current study, which provides mechanistic insight into how KEAP1 mutations rewire tumor metabolism and why glutamine deprivation results in growth suppression, these data provide critical pre-clinical evidence supporting the treatment of patients with KEAP1 mutations with glutaminase inhibitors

[DOI] [PubMed] [Google Scholar] Ilie A
[DOI] [PMC free article] [PubMed] [Google Scholar] Tan B.L, Norhaizan M.E, Liew W

Venables, W

melanocortin receptor research, pigmentation pathway models, receptor selectivity comparison