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Despite application of certain therapeutic interventions in clinical practice, such as antioxidants (vitamin E, vitamin C and N-acetylcysteine), anti-inflammatory (corticosteroids, non-steroidal anti-inflammatory drugs), Calcium Channel Blockers (verapamil, dantrolene) effective treatment for IRI remains challenging
Parkin, DJ-1, -synuclein and LRRK2 have also been shown to associate with the mitochondrion or impact upon its function, but the mechanisms involved remain unclear [14][17]
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Paracetamol metabolite concentrations following low risk overdose treated with an abbreviated 12-h versus 20-h acetylcysteine infusion
