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Signs of Correct Administration A successful B12 injection should cause: Minimal pain at the site A small bump that fades within an hour Mild redness or soreness that resolves within 24 hours If symptoms worsen (swelling, pain, fever, rash), consult a doctor immediately

There are a great number of biological mechanisms that seem to be implicated in the cognitive deficits induced by chemotherapy agents, including: direct neurotoxic effects, impaired neurogenesis or increased death of nervous cells, white matter abnormalities, inflammatory responses, oxidative stress and even alterations in the levels of sex and stress hormones (Sleurs et al., 2016

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