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Vitamin, mineral, and multivitamin supplementation to prevent cardiovascular disease and cancer: US Preventive Services Task Force Recommendation Statement

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Several critical knowledge gaps define the frontier of the field: Chronic and sub-lethal mechanistic toxicity: the current body of knowledge is overwhelmingly dominated by studies of acute exposure at high, often environmentally unrealistic, concentrations

While these interventions can significantly improve a patient's daily life and may slow disease progression, they do not reverse the underlying lung damage (emphysema or chronic bronchitis) characteristic of COPD

Schramm, K., Vassao, D