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Many nonsteroidal anti-inflammatory drugs such as aspirin or ibuprofen act by blocking COX-2, which is stimulated by many cytokines and growth factors [86]

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Severe hypokalaemia (low blood potassium) is rare but can develop in some cases, particularly in severe megaloblastic anaemia or in patients taking certain medications such as diuretics

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The regulatory effects of exercise and metformin on biomarkers in obesity: a focus on uric acid, irisin, adiponutrin, adropin, and copeptin

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10.1016/j.jmb.2006.06.026

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Until this day, the exact cause of the disorder remains unknown

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