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The enhanced susceptibility to the inflammatory insults in both TRKO and sD3KO mice reinforces the possibility that a more pronounced tissue inflammatory response can be elicited when TH metabolism is unbalanced

In addition to these external stresses, there are many intrinsic toxicants produced during physiological metabolism and pathological processes, including reactive oxygen species (ROS) and proinflammatory cytokines

Jiang, N

Snchez-Vidaa DI, et al

We observed that electrolyte leakage also reduced by 37% in WBPH+GABA plants compared with WBPH infested plants ( Figure 4E ), which strongly suggest that electrolytic leakage and ROS are correlated