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Nucleotides that are not encoded by the DNA and are added at VD (variablediversity)-minigene-element junctions and DJ (diversityjoining)-minigene-element junctions, thereby introducing new amino acids at these junctions

Additionally, blocking sialylation with pharmacological agents like ambroxol sensitizes the tumor to immune checkpoint blockade (ICB) therapies, such as anti-PD-1 and anti-CTLA4, significantly improving tumor control and extending survival in preclinical models

10.1007/s11064-023-03927-7 145 KuoM

Clinical investigations affirm its effectiveness in facilitating mucus clearance and enhancing lung function in such cases

A low concentration of vitamin E is frequently observed in cerebrospinal fluid (CSF)