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A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)

But the reverse that being oversupplied with B vitamins can cause weight loss does not have good evidence

Prepare the injection: Remove the cap from the needle and use the syringe to draw the appropriate amount of B12 from the vial

10.1046/j.1523-1755.63.s84.33.x 105 PersengievS

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