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ASOs are currently in clinical trials for C9orf72 , SOD1 , FUS , and coiled-coil-helix-coiled-coil-helix domain containing 10 ( CHCHD10 ) ALS [204]

Sugiura T, Kato S, Shimizu T, Wakayama T, Nakamichi N, Kubo Y, Iwata D, Suzuki K, Soga T, Asano M, Iseki S, Tamai I, Tsuji A, Kato Y

The higher labeled glucose derived from [ 13 C 3 ]propionate in fasting mice suggests an increased carbon flux from propionyl-CoA to glucose production, even in the absence of changes in PCC activity

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