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In humans, OCT1 is mainly expressed in the sinusoid membrane of hepatocytes, whereas in rodents, OCT1 is strongly expressed in the basolateral membrane of renal proximal tubule cells

But regarding the safety issues, only a few are in consideration (Rubin et al., 2001)

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[PubMed] [Google Scholar] Vecchiet L, Di Lisa F, Pieralisi G, et al
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