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In lupus-prone mice and SLE patients, GLS2 expression is reduced in CD4 + T cells, and GLS2 reduces ROS levels and promotes the ability of CD4 + T cells to produce IL-2 by demethylating the IL-2 gene (64)

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The oral BPC-157 capsule option is noteworthy for patients who prefer not to inject

In contrast, compared to placebo, semaglutide resulted in a 59% improvement in MASLD and an improvement in liver fibrosis, which slowed the progression of the disease [130]
