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Autophagy is generally considered as cell survival mechanism

Lower cellular levels contribute to age-related brain, heart, and immune function decline

doi: 10.1155/2013/685308 Summary Keywords radiotherapy, ferroptosis, radiotherapy sensitivity, radiation-induced injury, pharmacotherapy Citation Liu Y, Zhan J, Wang J, Zeng X, Liu S, Huang L, Niu L, Sun C, Ding Z, Xing Y, Zhou Z, Li X, Li Q and Wang H (2025) Ferroptosis: a double-edged sword that enhances radiation sensitivity and facilitates radiation-induced injury in tumors

2006, The National Academies Press, Washington, DC Whyte MP, Mahuren JD, Fedde KN, Cole FS, McCabe ER, Coburn SP: Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate