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Description
Disorders Associated with Tetrahydrobiopterin Synthesis and Salvage There are at least four identified disorders that manifest with BH 4 -deficient hyperphenylalaninemia designated as hyperphenylalaninemia, BH 4 -deficient type A (HPABH4A), HPABH4B, HPABH4C, and HPABH4D
286 :H1408H1415
A study investigated the impact of EGCG on cholinergic-like neurons (ChLNs) with the PRESENILIN 1 mutation E280A (PSEN1 E280A)
Guerra RM, Pagliarini DJ
Phosphorylation of IB by the IKK complex triggers its recognition by an E3 ligase complex which leads to its polyubiquitination and subsequent degradation by the proteasome
