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Limitations There are a couple of potential weaknesses of this study
Astrocytes are central to the brain maintenance through (1) controlling ionostasis of major ions (Na + , K + , Ca 2+ and Cl ) that define neuronal excitability

As the implanted tumour cells lack p53 expression (ID8 Trp53 / ), and p21 is a p53-dependent gene, we wanted to confirm that (a subset of) the p21-positive cells were tumour derived
More importantly, a combined antibacterial agent with an antibiotic and glutamine 12 , which is identified by metabolic state-driven approach, is being developed by Guangdong Litai Pharmaceutical Co., LTD., China

With pentadecapeptide BPC 157 application, rapid elimination of the increased pressure in the ligated superior sagittal sinus, the eliminated severe portal and caval hypertension and aortal hypotension, and rapid collateral vessels recruitment, counteracted multiorgan failure syndrome denotes the essential proof-of-principle