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And thats the other big concern

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Because DSIP primarily promotes slow-wave sleep, daytime drowsiness or grogginess can occur if the peptide disrupts normal sleep-wake patterns

The skin needs time to adapt

For example, turmeric oleoresin administration in pigs has been reported to reduce feed conversion efficiency (or weight gain), increase liver and thyroid weights, and result in histological alterations in the kidney, liver, and urinary bladder