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Besides, the fragment crystallizable (Fc) of the antibody can bind to Fc receptors (FcRs) on the surface of immune cells and induce ADCC, making it a three-functional antibody (Triomab) [195, 196]

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In addition, rodent models are essential in TBI research because they can accurately replicate various injury mechanisms, including penetrating injuries, contusions, and concussions that have clinical manifestations