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Description

Ten minutes of forebrain ischemia in adult rats led to a significantly decreased number of intact neurons in hippocampal tissue, decreased concentrations of glutathione and ATP, and increased total nitrate/nitrite and thiobarbituric acid-reactive substances which accumulate in conditions of oxidative stress [133]

Dialysis-related carnitine disorder and levocarnitine pharmacology

The study lasted 9 weeks, during which clinical signs associated with biotin deficiency and biochemical parameters, such as serum and tissue biotin levels (liver, kidney, brain, testes), and biotin-dependent enzyme activity of 3-methylcrotonyl CoA carboxylase (MCC), propionyl-CoA carboxylase (PCC), pyruvate carboxylase (PC) and acetyl-CoA carboxylase (ACC), and blood glucose levels, were evaluated